PHARMACEUTICAL DEVELOPMENT & ANTI-MICROBIAL STUDY (IN VITRO) OF TANKANAMRUTA MALAHAR W.S.R. TO RASA TARANGINI
Abstract
“Tankan†which is among the Kshar traya mentioned in “Kshar trik vidnyaniya trayodasha taranaga†of Acharya Sadananda Sharma virachit Rasa tarangini. Tankan i.e., Borax (Na2B4O7 10H2O) is composed of boric acid & soda. It is a salt of tetra Boric acid, an important compound of Boron, which is also known as sodium biborate. Other Rasa Vaidyas also have included “Tankan†under the groups of Ksharatraya, Ksharapanchaka, Dravaka gana, Mitra panchaka etc. The present study was conducted to develop “Tankanamruta malahar†(pharmaceutically & to study its antimicrobial activity (In vitro). “Tankanamruta malahar†is a good combination of herbo-mineral preparation, which is indicated in Dushta vrana shodhan chikitsa or infected wounds. Though this formulation is from Ayurvedic classical text but there is a need to develop the standard procedure of preparation as they have faster & accurate results than oral administration of drug, so by the fusion of modern instruments & traditional methods of manufacturing procedures we have tried to make “Tankanamruta malahar†which contains Shuddha Tankan bhasma, Siktha taila, Sarji kshar, Shuddha pushpa kasis & Pipal twak kshar. Standardization describes all measures taken during manufacturing process like Shodhan, Maran, Kshar nirman & Siktha taila preparation etc & quality control leads to reproducible quality of particular product & in vitro study was performed to evaluate its anti-microbial activity against selected pathogens.
