http://ijaprs.ijraps.in/index.php/ijapr/issue/feedInternational Journal of Ayurveda and Pharma Research2025-08-25T19:51:54+08:00Dr B Srinivasulu M.D (Ayu.)ijaprs@gmail.comOpen Journal Systems<div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong> is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of <strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong> systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div>http://ijaprs.ijraps.in/index.php/ijapr/article/view/3789Biodiversity and Ethnobotanical Study of Medicinal Plants in the Jageshwar Region, Almora District2025-08-20T10:02:27+08:00Diksha Bairwandikshabairwan123@gmail.comSuresh Chaubeysureshdr235@rediffmail.comR.C. Tiwaridikshabairwan123@gmail.comAsheesh Pandeydikshabairwan123@gmail.com<p>Jageshwar, located in the Almora district of Uttarakhand, India, is renowned for its ancient temple complex and dense forests dominated by Deodar trees (<em>Cedrus deodara</em>), locally called '<em>Devdaru</em>'. This study aims to identify, document, and promote the conservation of ethnomedicinal plants traditionally used by the local communities in this Himalayan region. Through extensive field surveys and ethnobotanical interviews, the research documents the indigenous knowledge associated with 20 medicinal plant species used to treat a variety of ailments. Key species identified include <em>Vinca major, Trachyspermum sprague, Berberis aristata</em> and <em>Rhododendron arboreum</em>. These plants are employed in the treatment of common illnesses such as cough, cold, fever, and skin infections, as well as chronic conditions like diabetes, asthma, and gastrointestinal disorders. The study not only highlights the therapeutic potential of these plants but also emphasizes the critical role traditional knowledge plays in sustaining primary healthcare in remote areas. Observations indicate a decline in plant availability due to deforestation, climate change, and increasing human activities. The ecological richness of the region, coupled with the cultural significance of its plant-based healing practices, underscores the urgent need for conservation efforts. The study advocates for sustainable forest management, afforestation programs, and responsible tourism to protect this fragile ecosystem. Moreover, it calls for further pharmacological research to validate the efficacy and safety of the documented traditional remedies<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3790Formulation and Evaluation of Fast Dissolving Oral Film of Sitagliptin Phosphate by Solvent Casting Method2025-08-20T10:02:28+08:00V. Sruthisrikanthreddyporeddy@gmail.comV. Alagarsamysrikanthreddyporeddy@gmail.comP. Subhash Chandra Bosesrikanthreddyporeddy@gmail.comD. Sarithasrikanthreddyporeddy@gmail.comP. Srikanth Reddysrikanthreddyporeddy@gmail.com<p>The primary objective of this study was to develop sitagliptin phosphate oral films that dissolve quickly in order to treat diabetic mellitus. The solvent casting method was employed to make the sitagliptin phosphate films that dissolve quickly. Film forming polymers HPMC E 15 and HPMC E 50 cps were utilised, along with plasticisers PEG and propylene glycol. We tested the films for stability, in-vitro disintegration time, in-vitro dissolving test, drug content, thickness, folding endurance, percentage elongation, tensile strength, and scanning electron microscopy. The outcomes met or exceeded expectations. Formulation 3 had the quickest disintegration time at 20 seconds and the fastest drug release time at 3 minutes out of all the formulations. From the data shown above, it can be inferred that Sitagliptin phosphate fast-dissolving oral films have the potential to increase absorption by bypassing the first-pass effect and producing quick action<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3791Pharmaceutical, Analytical and Chromatographic Evaluation of Ark Tail: An Ayurvedic Oil Formulation2025-08-20T10:02:28+08:00Adhao Mamata Pravinmamata.adhao@gmail.comNarvekar Mamata Vasantmamata.adhao@gmail.com<p><em>Arka Taila</em>, a classical Ayurvedic medicated oil formulation described in <em>Sharangadhara Samhita</em>, is traditionally used for the management of skin disorders such as <em>Vicharchika</em> (eczema), <em>Pama</em> (scabies), and <em>Kacchu</em> (itching). Despite its therapeutic significance, limited scientific research has been conducted on its pharmaceutical and analytical characterization.<strong> Materials and Methods: </strong><em>Arka Taila</em> was prepared using the <em>Sneha Kalpana</em> method with a standard ratio of 1:4:16 <em>(Kalka:Sneha:Drava)</em> incorporating <em>Haridra Kalka</em> (Curcuma longa), <em>Murchita Sarshapa Taila</em> (processed mustard oil), and <em>Arka Patra Swarasa</em> (Calotropis juice). <em>Murchana Sanskara</em> was performed as per classical texts to enhance the oil base. Pharmaceutical evaluation included observation of <em>Sneha Siddhi Lakshanas</em>. Organoleptic parameters, physicochemical tests (including refractive index, acid value, saponification value, iodine value, pH, etc.), and HPTLC profiling were carried out as per the standards of the Ayurvedic Pharmacopoeia of India. <strong>Results and Discussion: </strong>The formulation exhibited classical <em>Sneha Siddhi Lakshanas</em> confirming proper processing. Physicochemical parameters were within acceptable limits: refractive index (1.46729), acid value (1.245), iodine value (116.9), and peroxide value (1.02), indicating stability and purity. HPTLC profiling revealed multiple distinct phytochemical bands in <em>Arka Taila</em> that were absent in both <em>Amurchit</em> and <em>Murchit</em> mustard oil, validating the successful infusion of herbal and distillate bioactive components. <strong>Conclusion: </strong>The study validates the traditional preparation and pharmacological integrity of <em>Arka Taila</em> through modern scientific parameters. Its pharmaceutical stability, phytochemical richness, and favourable physicochemical profile support its continued therapeutic use and pave the way for further clinical and pharmacological investigations in dermatological applications<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3792Ayurvedic Management of Spinal Epidural Lipomatosis2025-08-20T10:02:28+08:00Cashmi Jeswindcashmijes2014@gmail.comAsha Karunakaran Kcashmijes2014@gmail.comSuneeshmon M Scashmijes2014@gmail.com<p>Spinal Epidural Lipomatosis (SEL) is a rare cause of Lumbar pain and Spinal canal stenosis due to an excessive amount of epidural fat in the Spinal canal. Conservative treatments generally aimed to decrease the thickness of adipose tissue in the epidural space, but the majority of patients tend to undergo surgical decompression to relieve neurological symptoms. The present study was aimed at treating a 23-year-old male patient admitted to the Government Ayurveda college, Thiruvananthapuram, who was diagnosed as Lumbar spinal canal stenosis due to Spinal Epidural Lipomatosis through MRI screening. While considering the etiopathogenesis of this disease, it cannot be correlated to a specific<em> Vyadhi </em>as per Ayurvedic classics<em>. </em>However, a line of treatment can be adopted by considering the <em>Vyadhi ghatakas, </em>such as<em> Srotovaigunya, Avarana Vata, as well as </em>diseases like <em>Gridrasi </em>and<em> Pakwashaya gata vata</em><em>. Pachana, Deepana, Snehana, Swedana,</em> and<em> Sodhana</em> were the treatment protocols adopted in this case. Here, these treatment protocols were found effective in treating Spinal epidural lipomatosis. Along with a review MRI screening, Modified Oswestry LBP Disability index (ODI), Swiss Spinal Stenosis scoring (SSS), and Visual Analogue Scale (VAS) were also used for assessment. Before treatment, ODI was 40% and reduced to 24% after treatment, and after a follow-up 2 months, it was reduced to 15%. SSS before treatment was 28 and reduced to 18 after treatment, and on follow-up reduced to 9. VAS score at the time admission was 10/10 and subsequently reduced to 4/10; on follow-up, it was 2/10<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3775Experimental Study to Evaluate the Efficacy of Vishadan Tail in Dinitrofluorobenzene Induced Eczema in Albino Mice with reference to Dushivishjanya Vicharchika2025-08-20T10:02:28+08:00Lokesh Bhagadkarlokeshbhagadkar7@gmail.comMamta Adhaolokeshbhagadkar7@gmail.com<p><em>Vicharchika</em>, a type of <em>Kshudra Kushtha</em> described in Ayurveda, closely resembles eczema in modern dermatology. It is a chronic inflammatory skin condition often triggered by impaired digestion and toxin accumulation (<em>Ama</em>), which may be linked to <em>Dushivisha</em>- subtle environmental and dietary toxins described in Ayurvedic texts. The present experimental study evaluates the efficacy of <em>Vishadan Tail</em>, a classical Ayurvedic formulation cited in <em>Gadanigraha,</em> for treating <em>Dushivishjanya Vicharchika</em> (eczema) using a DNFB-induced eczema model in Swiss albino mice. Mice were divided into four groups: normal control, disease control, standard (Betamethasone-treated), and <em>Vishadan Tail</em>-treated. The formulation, rich in herbs with <em>Kusthaghna, Vishaghna,</em> and <em>Kandughna </em>properties, was applied topically for 7 days. Macroscopic skin assessments and histopathological evaluations were performed. Results demonstrated a significant reduction in erythema, odema, and scaling in the <em>Vishadan Tail </em>group compared to the disease control group (p<0.001) with outcomes comparable to the standard treatment. Histopathology further confirmed reduced inflammation and cellular infiltration. The study concludes that <em>Vishadan Tail</em> exhibits promising therapeutic potential in the management of eczema, supporting its traditional claims and suggesting its possible use as a safe herbal alternative in dermatological care<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3776Kshara Kalpana According to Rasatarangini: A Textual Review2025-08-20T10:02:28+08:00Gadekar Shubhamdrshubhamgadekar@gmail.comTaviad Krushnkumardrkrishnat@gmail.comKalsariya Bharatdrbharat1977@gmail.com<p><em>Kshara </em>(alkaline preparation) is widely used in various formulations as well as in various pharmaceutical procedures internally as well as externally. It also has therapeutic and surgical efficacy and shows results even when used in small doses. <strong>Aim</strong>: The present work aims to collect and summarize the information regarding <em>Kshara</em> <em>Kalpana</em> from Rasatarangini. <strong>Material</strong> <strong>and</strong> <strong>methods</strong>: Critical review of <em>Kshara</em> from Rasatarangini in various aspects such as its synonyms, properties, action on <em>Dosha</em>, <em>Kshara</em> prescribed in various formulations, percentage of <em>Kshara</em> in the formulation, other herbs used in the formulation, dose, indications, <em>Kshara</em> prescribed in various pharmaceutical procedures, and its practical application. <strong>Results</strong>: Rasatarangini describes 13 <em>Kshara</em> with <em>Vata</em>-<em>Kaphaghna</em> properties, <em>Swarjikakshara</em> having the most synonyms (16). They are vital in pharmaceutical processes, with usage varying from <em>Trikshara</em> (<em>Yavakshara</em>, <em>Swarjikakshara</em>, <em>Tankana</em>) at 16.6% each in <em>Parada</em> <em>Shodhana</em> to 25% <em>Tankana</em> in <em>Abhraka</em> <em>Satvapatana</em>. The text details 18 <em>Kshara</em>-containing formulations, such as <em>Gandhakadya</em> <em>Malahara</em> (0.43% <em>Tankana</em>) and <em>Shrisiddha</em> <em>Hinguleshwara</em> (50% <em>Tankana</em>). Additionally, 11 <em>Kshara</em> <em>Aamayika</em> <em>Prayogas</em> (practical applications) are noted, where <em>Ksharas</em> are combined with <em>Bhasmas</em>. Rasatarangini indicates these compounds for conditions like <em>Gulma</em> (abdominal lump) (11) and <em>Drushta</em> <em>Vrana</em> (infected wound) (7). Preparations use both traditional and modified methods, including <em>Nimbukamliya</em> <em>Kshara</em>. Typical doses are 2–12 <em>Gunja</em> (250 mg - 1.25 g), highlighting their significant role in Rasashastra. <strong>Conclusion</strong>: <em>Kshara </em>in Rasatarangini serves key therapeutic and pharmaceutical roles. This review gives to enrich existing knowledge and provide insights for researchers in this field of education and study.</p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3657Junk Food as Virudhahara: An Ayurvedic Perspective on Modern Dietary Incompatibilities and Health Risks2025-08-25T19:51:54+08:00Pooja Rameshmidhunpooja1316@gmail.comPrasanth S Rayuprasanth@gmail.com<p><em>Virudhahara</em>, or incompatible food, is a foundational concept in Ayurveda that refers to food combinations or preparations which disturb the equilibrium of the <em>Doshas </em>but do not facilitate their elimination, thereby leading to the accumulation of toxins (<em>Ama</em>) and the onset of disease. This paper explores the concept of <em>Virudhahara</em> in the context of rising global consumption of junk food. Junk foods, characterized by high levels of sugar, salt, unhealthy fats, preservatives, and low nutritional value mirror many types of dietary incompatibilities described in Ayurvedic texts, such as <em>Agni Virudha</em> (incompatibility with digestive fire), <em>Samyoga Virudha</em> (wrong food combinations), <em>Samskara Virudha</em> (improper food processing), and <em>Satmya Virudha</em> (incompatibility with one’s habit or constitution). The study conducts a critical review of Ayurvedic classical references and correlates them with contemporary definitions and harmful effects of junk food consumption. It discusses the physiological mechanisms through which <em>Virudhahara </em>leads to <em>Agnimandya</em>, <em>Ama</em> formation, <em>Srothorodha</em>, and eventual manifestation of systemic disorders such as obesity, diabetes, cardiovascular disease, neurological conditions, and even cancer. The review also identifies factors that can mitigate the effects of <em>Virudhahara </em>and outlines classical Ayurvedic treatments like <em>Shodhana</em> (purification), <em>Shamana</em> (palliative therapies), and <em>Rasayana</em> (rejuvenation). By drawing parallels between ancient Ayurvedic wisdom and modern dietary trends, this paper emphasizes the urgent need to re-evaluate current eating habits and adopt preventive strategies rooted in traditional health science<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3767Ayurvedic Management of Uterine Fibroid2025-08-20T10:02:28+08:00Behera Swetanjaliswetanjalibehera21@gmail.comMeher Sudeshnadrsmeher@gmail.comSamal Jitendradrjsamal@gmail.com<p>Fibroid is the most common benign solid tumour of the uterus in female. Histologically, this tumour is composed of smooth muscle and fibrous connective tissue, so named as Uterine leiomyoma, myoma or fibromyoma. According to the U.S. National Institutes of Health (NIH) 20-25% of women of reproductive age have fibroids. The aetiology still remains unclear. The prevailing hypothesis is that, it arises from the neoplastic single smooth cells of the myometrium. It can be related to <em>Garbhasaya Granthi </em>or<em> Arbuda</em>. The presented case involves a 43 years old female patient who approached the outpatient department with complaints of menorrhagia with clots and pain in left iliac region. On the basis of sign and symptoms, USG had shown bulky uterus measuring 9.6×4.6×6.6cm and a mixed echoic mass measuring 3.3×2.4cm seen in middle part of uterus, which is a fibromyoma. After having a thorough examination, the patient underwent Ayurvedic treatment protocol, including <em>Sodhana chikitsa</em>, oral medication and dietary modifications. After three months, the patient reported symptomatic relief and an ultrasound report with size of uterus i.e. 8.2×5.5×4.4 cm and a small intramural fibroid of size 15mm<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3780Unveiling the Forgotten Rasaushadha: A Critical Review of ‘Vadavanala Ras’ as Mentioned in Rasa Yoga Sagara2025-08-20T10:02:28+08:00Vuyyuru Srikanthsrikanthvuyyuru3@gmail.comKovi Sreeharidr.skovi@gmail.com<p><em>Vadavanala Ras</em> is an herbomineral preparation mentioned in various Ayurveda classical books. <em>Vadavanala Ras</em>, a mysterious and elusive Ayurvedic formulation, has long been shrouded in obscurity. Despite its potential therapeutic benefits, this ancient remedy has been largely overlooked in modern times, with no available commercial preparations or comprehensive literature reviews. This article aims to resurrect the knowledge of <em>Vadavanala Ras,</em> delving into its historical context, pharmacological properties, and potential clinical applications. <em>Rasayoga Sagara</em> of – century has mentioned 26 distinct formulations of <em>Vadvanala Ras</em> that is presently unavailable in market. This pioneering study seeks to revive interest in this forgotten gem, encouraging further research and development of <em>Vadavanala Ras </em>as a valuable addition to the Ayurvedic pharmacopeia<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3795Evaluation of Sagala Noi Chooranam - A Review of its Therapeutic Potential2025-08-20T10:29:45+08:00P. Karthikdrkarthik7476@gmail.comJ. Sriramdrkarthik7476@gmail.comK. Shyamaladrkarthik7476@gmail.comT. Maharasi Maniselvidrkarthik7476@gmail.com<p>The uniqueness of Siddha medicine lies in its holistic approach- the physical, mental, social and emotional well-being are fostered by adopting appropriate lifestyle practices, dietary regimens, safe and effective drugs sourced from the surroundings and therapies specific to this system. The medicine called <em>Sagala noi chooranam</em> is one among the Siddha medicines mentioned in the book <em>Brahmamuni karukkidai soothiram 390</em>. The drug review of the medicine explains about morphology, family, chemical constituents and pharmacological actions of each ingredient. The main sources of review as Siddha text and resources from the database and relevant journals. The main aim of the study is to evaluate the chemical characters and action of the drug <em>Sagala noi chooranam</em>. The secondary aim is to spread awareness about the drug. The conclusion suggests that <em>Sagala noi chooranam</em> may possess therapeutic benefits, but further research is needed to establish its efficacy and safety<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3794Poduthalaiyathy Kudineer: A Review of its Therapeutic Potential2025-08-20T10:02:28+08:00G. Pandipriyapandipriya.g97@gmail.comK. Ramyaramyakuppusamy91@gmail.comA. Anbumalaranbumalara@gmail.comT. Maharasi maniselviselvimaharasi@gmail.com<p>Siddha, a traditional system of medicine, leverages the therapeutic potential of herbs and natural substances to promote holistic health. In Siddha medicine, <em>Maantham</em> is categorised under <em>Aga Karana Noigal, </em>encompassing 21 types, including <em>Por Maantham</em>. The signs and symptoms of <em>Por Maanthan</em> are correlated with acute diarrhoeal disease. <em>Poduthalaiyathy Kudineer</em>, a classical Siddha polyherbal formulation, is traditionally used to treat <em>Por Maantham</em>, a condition akin to acute diarrhoeal disease. This comprehensive review aims to explore the therapeutic potential of <em>Poduthalaiyathy Kudineer</em> in managing <em>Por maantham</em> (acute diarrhoeal disease). Diarrhoea in children is a common and significant health issue worldwide, particularly in developing countries. It can lead to dehydration, electrolyte imbalance, malnutrition, and even death if left untreated or poorly managed. Children under the age of five are most vulnerable to diarrhoeal diseases due to their developing immune systems and increased exposure to pathogens. Effective management and prevention strategies are crucial to reducing the morbidity and mortality associated with diarrhoeal diseases in children. A thorough examination of traditional Siddha texts and contemporary scientific literature was conducted to elucidate the formulation’s composition, mechanism of action and efficacy. The review highlights the synergistic potential of <em>Poduthalaiytahy kudineer’s </em>multi-herbal components, which may contribute to its efficacy in managing acute diarrhoeal disease<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3796Evaluation of Iypathi Chooranam - A Review of its Therapeutic Potential2025-08-20T10:31:39+08:00K. Ramyaramyakuppusamy91@gmail.comG. Pandipriyaramyakuppusamy91@gmail.comA. Anbumalarramyakuppusamy91@gmail.comT. Maharasi Maniselviramyakuppusamy91@gmail.com<p>Siddha medicine is one of the traditional originating from south India, offers a unique approach to the diagnosis and treatment of eye disease <em>(Kannoigal),</em> based on the foundational concepts of <em>Pancha bootham</em> and three bodily humours <em>(Vali, Azhal, Iyyam)</em>. The medicine called <em>Iypathy Chooranam</em> is one among the siddha medicine mentioned on the book <em>Agasthiyar nayana vithi</em>. The drug review of the medicine explains about morphology, family, chemical constituents and pharmacological actions of each ingredient. The main sources of review as siddha text and resources from the database and relevant journal. The main aim of the study is to evaluate the chemical characters and action of the drug <em>Iypathi chooranam</em>. Secondary aim is to spread consciousness about the drug. The conclusion suggest <em>Iypathi chooranam</em> may possess therapeutic benefits, but further research is needed to establish its efficacy and safety<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3799Phytochemical Analysis of Iypathi Chooranam2025-08-20T10:02:29+08:00K. Ramyaramyakuppusamy91@gmail.comP. Karthikdrkarthik7476@gmail.comK. Shyamalashyamsujisathya@gmail.comT. Maharasi Maniselviramyakuppusamy91@gmail.com<p><em>Iypathi Chooranam</em> is a traditional polyherbal formulation used in the Siddha system of medicine, reputed for its therapeutic efficacy in managing ailments such as fever, skin disorders, gastrointestinal disturbances, eye diseases. The present study aims to evaluate the phytochemical profile of <em>Iypathi Chooranam</em> through preliminary screening techniques to establish its pharmacological potential. The formulation was prepared as per classical Siddha texts <em>Agasthiyar nayana vithi </em>and subjected to successive extraction using solvents of increasing polarity hexane, ethyl acetate, ethanol, and water. Each extract was then analyzed for the presence of major phytoconstituents, including alkaloids, flavonoids, tannins, saponins, glycosides, terpenoids, and phenolic compounds, using standard qualitative phytochemical methods. The results revealed the compounds known for their antioxidant, antimicrobial, and anti-inflammatory properties. The presence of alkaloids and saponins further supports the traditional claims of its therapeutic efficacy. This phytochemical profiling provides a foundational understanding of <em>Iypathi Chooranam</em> bioactive potential and supports its continued use in traditional medicine. This research contributes to the growing scientific validation of Siddha formulations and supports their integration into evidence-based complementary medicine. This analysis helps to explore the properties of medicine in their usage in clinical studies. It is concluded that the presence of certain phytochemicals justifies the better use of the medicine <em>Iypathy chooranam</em> for eye diseases<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3769Ayurvedic Management of Ovulatory Dysfunction in PCOS2025-08-20T10:02:29+08:00Giby Thomasgibythomasdr@gmail.comAnjali TSanjalimeganath@gmail.comArchana Asokanjalimeganath@gmail.com<p>Polycystic ovarian syndrome, is a common endocrine disorder in women of reproductive age that can lead to anovulation. This disorder accounts for 30% of all infertility cases with 73% of them suffering from infertility due to anovulation. This is a case report of 31-year old female complaining of scanty and painful menstruation. As she had a history of missed abortion at 6<sup>th</sup> week of gestation she was advised for ultrasound scan and her scan revealed bilateral polycystic ovarian syndrome. She also had anovulatory cycles on her follicular study. The treatment given aimed at correcting <em>Vata kapha dushti, Agni mandya</em> and <em>Srotorodha</em>. In this condition, <em>Samana </em>and<em> Sodhana</em> therapies were given. <em>Samana chikitsa</em> helped in <em>Agni deepana </em>and for normalising <em>Vata kapha</em>. Whereas <em>Sodhana chikitsa</em> helped in removing <em>Srotorodha</em>. Following that, <em>Artava janaka dravyas </em>and<em> Rasayana chikitsa </em>were given, which helped in correcting the <em>Artava kshaya </em>and proper <em>Dhathu</em> formation. The whole treatment may have contributed to accelerated maturation of graafian follicles. Thus the follicle ruptured and ovulation was detected in follicular study which highlights the potential action of ayurvedic treatment modalities in anovulatory cycles due to polycystic ovarian syndrome<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3630A Conceptual Analysis on Efficacy of Triphala Madhu Ghrita in Vision Enhancement2025-08-20T10:02:29+08:00Anusha D.Panushadp219@gmail.comAmrutha Pamruthap918@gmail.comReshma Tdrreshmaarjun@gmail.comS P Sailysailymurali@gmail.com<p><em>Triphala</em> composed of <em>Amalaki, Bhibhitaki </em>and<em> Harithaki</em> is a <em>Tridoshic rasayana</em> known for its rejuvenating properties and effectiveness in preventing and managing eye disorders. Ayurvedic texts emphasize the importance of <em>Dinacharya</em> (daily regimen), <em>Rathricharya</em> (night regimen), <em>Sadvritta </em>(ethical practices) and <em>Rtucharya</em> (seasonal regimen) for maintaining health with <em>Triphala</em> being a key component in these practices. The combination of <em>Triphala</em> with <em>Madhu</em> (honey) and <em>Ghrita </em>(ghee) has the ability to nourish as well as protect the eyes. <em>Madhu</em> with its anti-inflammatory, anti-microbial and antioxidant properties complement <em>Triphala</em> by supporting eye health and reducing inflammation. <em>Ghrita</em> (ghee) particularly <em>Go ghrita </em>(cow’s ghee) supports the absorption of active ingredients and nourishes the ocular surface. This formulation has demonstrated potential in preventing cataracts, reducing oxidative stress and improving overall vision. Additionally, the anti-inflammatory and antimicrobial properties of <em>Triphala</em> help manage conditions like conjunctivitis and blepharitis. This article explores the therapeutic potential of the combination of <em>Triphala, Madhu</em> and <em>Ghrita</em> in maintaining eye health and preventing degenerative eye conditions particularly age-related issues such as cataracts<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3762An Overview of Potential Benefits of Ashwagandha (Withania Somnifera) in Prevention and Treatment of Cervical Cancer2025-08-20T10:02:29+08:00Gupta Garimagarimag755@gmail.comK. Bharathibaruhunt@gmail.comMalsariya Swatiswatimalsariya@gmail.com<p>Cervical cancer is the fourth most common cancer affecting women worldwide and the second most prevalent among women in India, following breast carcinoma, with an estimated 127,526 new cases annually. Despite advancements in screening and treatment, recurrent and persistent forms of cervical cancer pose a significant therapeutic challenge. Conventional therapies often come with considerable toxicity, limited efficacy in advanced stages, and poor accessibility in low-resource settings. Therefore, there is an urgent need for safer, multi-targeted therapeutic alternatives. In recent years, <em>Ashwagandha</em> is one among the herbal drugs of Ayurveda found useful in different cancers. <em>Ashwagandha</em> leaf is rich in an active principle called withaferin A. Withaferin A (WFA), a steroidal lactone has shown significant anti-neoplastic activity across various cancer cell lines, including cervical cancer, in both in vitro and in vivo models. This paper reviews the anticancer efficacy of Withaferin A in cervical cancer and, for the first time, explores the broader therapeutic potential of <em>Ashwagandha</em> through an integrative perspective. Emphasis is placed on its anti-proliferative, anti-inflammatory, pro-apoptotic, and adaptogenic properties. The potential mechanism of action are also examined through the lens of <em>Panchmahabhautika Sanghatana</em>- the Ayurvedic five-element theory- providing a holistic perspective on <em>Ashwagandha </em>impact on cellular pathology. This integrative approach not only bridges traditional Ayurvedic concepts with contemporary biomedical research but also opens a promising pathway for the development of low-toxicity, plant-based therapies for cervical cancer<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3705Integrative Perspectives on Obesity Management: Bridging Ayurveda and Modern Nutrition for Sustainable Health Outcomes2025-08-20T10:02:29+08:00Arun Pratapdr.arunpratap@gmail.comSuvendu Routdrsrout@gmail.com<p>Obesity, a multifactorial disorder characterized by excessive accumulation of adipose tissue, poses a global health burden with significant implications for metabolic, cardiovascular and endocrine systems. While conventional approaches focus on calorie restriction and pharmacological interventions, they often fall short due to individual variability, poor sustainability and inadequate attention to systemic imbalances. Ayurveda, the traditional Indian system of medicine, offers a comprehensive and individualized approach to obesity, conceptualized as <em>Sthaulya</em>, a condition primarily involving <em>Kapha Dosha</em> imbalance, <em>Medodhatu</em> accumulation along with impaired <em>Agni</em> (digestive/metabolic fire). This pathophysiological model highlights the interplay between digestion, metabolism, tissue nourishment and psychosomatic factors. Ayurvedic dietary principles emphasize the consumption of <em>Laghu</em> (light), <em>Ruksha</em> (dry) and <em>Ushna</em> (hot) foods, alongside mindful eating practices and metabolic-enhancing spices, aligning with modern concepts of glycemic control, gut health and circadian eating. Treatment strategies include <em>Shodhana</em> (detoxification), <em>Shamana</em> (palliation) and lifestyle interventions <em>(Vyayama, Dinacharya),</em> supplemented by potent herbal and mineral formulations. Key agents such as <em>Guggulu, Loha</em> <em>Bhasma, Shilajatu, Guduchi, Musta</em> and <em>Triphala</em> exert anti-obesity, anti-inflammatory and metabolic regulatory effects while supporting sectional nutrition-the targeted nourishment of specific tissues and organ systems compromised in obesity. By addressing the root causes and maintaining systemic harmony, Ayurveda provides a sustainable framework for obesity management. Integrating traditional Ayurvedic wisdom with modern nutritional and biomedical sciences offers a promising path toward personalized, holistic and long-term solutions for the obesity epidemic<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3793An Ayurvedic Approach to Secondary Amenorrhea as a Manifestation of Premature Ovarian Failure (POF)2025-08-20T10:02:29+08:00Narendra Kumar Meenalipakshi0798@gmail.comLipakshi Agrawallipakshi0798@gmail.comDiksha Khathurialipakshi0798@gmail.com<p>Amenorrhea, the absence of menstruation, is categorized into primary (before menarche) and secondary (after menarche) forms, with significant implications for female reproductive health. Secondary amenorrhea in women of reproductive age may be an indication of an undiagnosed, chronic condition and appropriate treatment is dependent upon accurate diagnosis of the underlying aetiology. According to <em>Acharya Sushruta</em>, Secondary amenorrhoea is described as destruction of <em>Artava (Nashtartava</em>) as well as described it as one of the symptoms of <em>Artava-Vaha Stroto Viddha Lakshana</em>, where he describes that mechanical injury to <em>Garbhashaya</em> i.e. uterus may lead to <em>Artavanasha </em>which means secondary amenorrhoea, this results in infertility. Here, we have described a case study of secondary amenorrhoea due to Premature Ovarian Failure. A 40-year-old married woman came to our OPD of Prasuti Tantra & Stri Roga, M.M.M. Govt. Ayurveda College, Udaipur. with the presenting complaints of absence of menses for 1.5 years, inability to conceive for 18 years. After taking patient history, general examination in which blood pressure (158/110mm hg), BMI (28.1kg/m<sup>2</sup>) were raised, and thorough investigations reveals there is altered echotexture of uterus with small uterine fibroid in USG we considered the POF as a main cause of <em>Nashtartava </em>(secondary amenorrhoea) and treated with <em>Matra Basti </em>with<em> Lashuna taila </em>and oral intake of<em> Panchkola Churna, Punarnava Mandoora</em>, <em>Balsudha combination</em>, <em>Kaishora Guggulu, Dashmoola Kwatha </em>and got surprising result in secondary amenorrhoea due to POF. The findings also emphasize the need for further research to evaluate long-term outcomes and refine management protocols for both primary and secondary amenorrhea, ultimately aiming to improve patient care and fertility prospects<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3777Ayurvedic Management of Adenoid Hypertrophy in Children2025-08-20T10:02:29+08:00Arun Bathirasukrutham15@gmail.comAthira Sathirasukrutham15@gmail.com<p>Upper airway obstruction in children remains a concern and one of the most common causes is attributed to adenoid hypertrophy is the reason. The cause is mostly attributed to an increased response to immunologic activity. The prevalence in children has been estimated at 34.5%. The clinical manifestation of adenoid hypertrophy is varied in children and can be accompanied by various comorbidities. Upper airway obstruction usually leads to mouth breathing, nasal diseases, asthma and other symptoms. If not managed properly it can lead to serious conditions like sleep apnea, cognitive impairment and altered craniofacial growth. A relatively common management in the condition is adenoidectomy. Reluctance of common people to surgery necessities an alternative and novel non-surgical approach to deal this condition, in which Ayurveda can showcase its value. The disease <em>Kanthashaluka</em> is one of the seventeen diseases affecting the throat mentioned is <em>Mukharoga prakarana </em>(chapter on diseases of mouth). Adenoid hypertrophy and <em>Kanthashaluka</em> has similar clinical features and the basic diagnosis and line of management is based on <em>Kanthasaluaka</em>. This is a single case study of a 7 years 9 months old child with grade 4 adenoid hypertrophy managed with Ayurvedic medicines. The after endoscopy revealed grade 2 adenoid. Proper medicines based on the stage of condition following the basic principles in <em>Kasa swasa chikitsa</em> (treatment of respiratory disorders) and <em>Kanta roga chikitsa </em>(treatment of throat diseases) can provide an effective management in the condition<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3770Ayurvedic Approach in Thoracic Myelopathy2025-08-20T10:02:29+08:00Febina NCncfebina@gmail.comSivakumar C.S csdrsivakumar@yahoo.inAneesh Sdraneeshkerala@gmail.com<p>Thoracic myelopathy is a disorder characterized by spinal cord compression occurring in the thoracic region of the spine. It is relatively rare due to the limited degenerative changes that occur at this level of the spine, largely because the rib cage restricts movement in that area. A 54-year female patient complaint of burning pain over bilateral foot since 1 year and aggravated since 3-4 months, weakness of bilateral lower limbs for 3 months, loss of sensation over lower back, lower abdomen, bilateral lower limbs for 2weeks, urinary retention and feacal incontinence for 2 weeks came to the OPD of our hospital. The condition was diagnosed as thoracic compressive myelopathy through clinical examination and MRI spine. On the basis of clinical feature condition is similar to <em>Kaphavrutha vata</em> in Ayurveda. Patient underwent Ayurvedic treatment modalities <em>Rooksha swedam </em>(dry sudation using medicinal powder<em>), Sankara sweda, Dasamoola kashaya dhara, Abhyangam </em>(oil massage)<em>, Matravasthi </em>(oil enema) and<em> Kayasekam</em>. After treatment symptoms reduced and Sensory, motor and autonomic functions improved. The treatment outcome suggests that ayurvedic treatment modalities can be a valuable alternative management for spinal cord disorder<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3797Enlightening on Effectual Ayurvedic Therapeutics in Early Diagnosed Type 2 Diabetes Mellitus2025-08-20T10:02:29+08:00Acharya Manishshuddhi.research@jeenasikho.co.inGitika Chaudharyshuddhi.research@jeenasikho.co.inRichashuddhi.research@jeenasikho.co.inNavneet Kaurshuddhi.research@jeenasikho.co.inTanu Ranishuddhi.research@jeenasikho.co.in<p>Diabetes mellitus is a lifestyle-related disease that has been recognized and described in Ayurvedic literature since ancient times. It is termed as <em>Prameha vyadhi</em> in Ayurveda. The characteristic symptom of the DM (<em>Prameha</em>) is polyurea (<em>Bahu mutrata</em>). It mainly causes due to <em>Kaphaprakopak aahar-vihar</em>. Due to this metabolic dysfunction occurs and it hampers the healthy life of a person. It affects both mental and physical health. This case study is about the male patient of age 38 years old. He came with early diagnosed type 2 diabetes to Jeena Sikho Lifecare Limited Clinic, Sangrur, Punjab on 30/11/2023. He had complaints like burning sensation in eyes, tingling numbness in legs etc. On the basis of Ayurvedic criteria he was diagnosed as <em>Pittanubandhi Kaphaj Prameha</em>. Ayurvedic treatment not only includes medications but also includes do’s and don’ts for diet and lifestyle (<em>Pathya-apathya</em>). Various drugs like <em>Haridra</em>, <em>Amalaki, Shilajeet </em>etc. are used in the above-mentioned case. This study enlightens that how <em>ayurvedic</em> treatment can reverse the diabetes if it is diagnosed early. Investigation reports reveal a catching reduction in HbA1c and mean blood glucose level after treatment. This ongoing case study enlightens the effectual Ayurvedic therapeutics for diabetes<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Researchhttp://ijaprs.ijraps.in/index.php/ijapr/article/view/3798Influential Effect of Diet and Panchakarma Therapy in Liver Disease: A Case Study Especially Referencing to the Vataja Yakrita Vikara2025-08-20T10:02:29+08:00Acharya Manishshuddhi.research@jeenasikho.co.inGitika Chaudharyshuddhi.research@jeenasikho.co.inRichashuddhi.research@jeenasikho.co.inSiddharth Charanshuddhi.research@jeenasikho.co.inTanu Ranishuddhi.research@jeenasikho.co.in<p>Ayurveda can offer promising improvement in liver diseases within a short period of time. Currently, there is a rapid rise in chronic liver disease (CLD) cases due to factors like alcohol intake, viral infections, and poor dietary habits. The most common cause nowadays is a long-term unhealthy lifestyle. In Ayurveda, <em>Yakrit Vikara</em> are described across various chapters and are considered disorders of <em>Raktavaha Srotas</em>. As the liver plays a key role in digestion and metabolism, liver disorders often present with digestive symptoms. This article presents a case of a 33-year-old male who visited Jeena Sikho Lifecare Limited Hospital, Jodhpur, Rajasthan, on 09/09/2024, with complaints of indigestion, constipation, and body pain. His liver function test showed elevated SGOT and SGPT levels. He had not started any modern medicine. Based on Ayurvedic assessment, he was admitted for <em>Panchakarma</em> therapy followed by a DIP diet. After 16 days of treatment, a positive improvement in LFT values and clinical symptoms was observed<em>.</em></p>2025-08-15T00:00:00+08:00Copyright (c) 2025 International Journal of Ayurveda and Pharma Research